Detalhe da pesquisa
1.
Transporter Activity Changes in Nonalcoholic Steatohepatitis: Assessment with Plasma Coproporphyrin I and III.
J Pharmacol Exp Ther
; 376(1): 29-39, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33127749
2.
Endogenous Plasma Kynurenic Acid in Human: A Newly Discovered Biomarker for Drug-Drug Interactions Involving Organic Anion Transporter 1 and 3 Inhibition.
Drug Metab Dispos
; 49(12): 1063-1069, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34599018
3.
Detection of Weak Organic Anion-Transporting Polypeptide 1B Inhibition by Probenecid with Plasma-Based Coproporphyrin in Humans.
Drug Metab Dispos
; 48(10): 841-848, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32723847
4.
Evidence for the Validity of Pyridoxic Acid (PDA) as a Plasma-Based Endogenous Probe for OAT1 and OAT3 Function in Healthy Subjects.
J Pharmacol Exp Ther
; 368(1): 136-145, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30361237
5.
Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity.
J Immunol
; 198(3): 1308-1319, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28003376
6.
Effect of pretreatment regimens of 1-aminobenzotriazole on metabolism and gastric emptying of probe compounds in rat.
Xenobiotica
; 49(6): 646-654, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29898636
7.
Coproporphyrin-I: A Fluorescent, Endogenous Optimal Probe Substrate for ABCC2 (MRP2) Suitable for Vesicle-Based MRP2 Inhibition Assay.
Drug Metab Dispos
; 45(6): 604-611, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28325716
8.
Estimation of the unbound brain concentration of P-glycoprotein substrates or nonsubstrates by a serial cerebrospinal fluid sampling technique in rats.
Mol Pharm
; 11(2): 477-85, 2014 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24380373
9.
Role of hepatic blood flow and metabolism in the pharmacokinetics of ten drugs in lean, aged and obese rats.
Xenobiotica
; 44(12): 1108-16, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24947446
10.
A modified serial blood sampling technique and utility of dried-blood spot technique in estimation of blood concentration: application in mouse pharmacokinetics.
Eur J Drug Metab Pharmacokinet
; 37(1): 23-30, 2012 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21948266
11.
A Tribute to Professor Saranjit Singh - A Critical Thinker, Innovator, Mentor, and Educator.
J Pharm Sci
; 111(5): 1224-1231, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34699842
12.
Conformational-Analysis-Guided Discovery of 2,3-Disubstituted Pyridine IDO1 Inhibitors.
ACS Med Chem Lett
; 12(7): 1143-1150, 2021 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34267885
13.
Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis.
ACS Med Chem Lett
; 11(7): 1402-1409, 2020 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32676146
14.
In Vitro Stimulation of Multidrug Resistance-Associated Protein 2 Function Is Not Reproduced In Vivo in Rats.
Pharmaceutics
; 10(3)2018 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30096834
15.
Endogenous Biomarkers to Assess Drug-Drug Interactions by Drug Transporters and Enzymes.
Curr Drug Metab
; 18(8): 757-768, 2017 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28738769
16.
Unmasking the Role of Uptake Transporters for Digoxin Uptake Across the Barriers of the Central Nervous System in Rat.
J Cent Nerv Syst Dis
; 9: 1179573517693596, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28469522
17.
Insight into tissue unbound concentration: utility in drug discovery and development.
Curr Drug Metab
; 14(3): 324-40, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23167621